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“Our research investigates how addictive drugs like cocaine, opioids, and nicotine change the brain to produce compulsive drug-taking and -seeking behaviors.” Lab Art by Antonia Caffrey

News Grace Zhang Presents Research on Biased GLP-1 Agonist for Substance Use DisordersGrace Zhang presented a poster at the Mid-Atlantic Pharmacology Society 2025 Conference at the Smilow Center for Translational Research at the University of Pennsylvania. Working with collaborators Antonia … Read More

ResearchLab Fun

Selected Publications 2025 Aranäs C, Caffrey A, Edvardsson CE, Schmidt HD, Jerlhag E (2025) Semaglutide suppresses cocaine taking, seeking, and cocaine-evoked dopamine levels in the nucleus accumbens.European Neuropsychopharmacology. 2025 Jul. PMID: 40644799. Caffrey A, Lavecchia E, Chichura KS, Hayes MR, … Read More

Principal Investigator Heath D. Schmidt, Ph.D. Dr. Heath D. Schmidt is the Killebrew-Censits Chair of Undergraduate Education and a Professor of Neuroscience & Pharmacology in the Schools of Nursing and Medicine at Penn. As a neuropharmacologist and Director of the … Read More

“To see what is in front of one’s nose needs a constant struggle” - George Orwell Novel roles for peripheral metabolic factors in substance use disorders Given that the search for effective pharmacotherapies for cocaine use disorder has, thus far, been fruitless, … Read More