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“Our research investigates how drugs of abuse like cocaine, prescription opioids, and nicotine change the brain to produce addiction-like behaviors.” Lab Art by Antonia Caffrey

News Dr. Schmidt Interviewed by the Scientific American“Semaglutide’s story becomes even more complicated in drug addiction. Addictive drugs such as cocaine and opioids are generally thought to “hijack” the brain’s natural reward pathways, says Heath Schmidt, a neuropharmacologist at the … Read More

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Selected Publications 2023 Schmidt HD, Zhang Y, Xi J, Zanni G, Liu R, Barr GA (2023) A new formulation of dezocine, Cyc-dezocine, reduces oxycodone self-administration in female and male rats . Neuroscience Letters. PMID: 37714288. Caffrey A, Lavecchia E, Merkel … Read More

Principal Investigator Heath D. Schmidt, Ph.D. Dr. Heath D. Schmidt is the Killebrew-Censits Chair of Undergraduate Education and a Professor of Neuroscience & Pharmacology in the Schools of Nursing and Medicine at Penn. As a neuropharmacologist and director of the … Read More

“To see what is in front of one’s nose needs a constant struggle” - George Orwell Novel roles for peripheral metabolic factors in substance use disorders Given that the search for effective pharmacotherapies for cocaine use disorder has, thus far, been fruitless, … Read More